ea0041ep989 | Thyroid (non-cancer) | ECE2016
Arpaci Dilek
, Celik Sevim Karakas
, Can Murat
, Gunes Gunes Cakmak
, Kuzu Fatih
, Unal Mustafa
, Bayraktaroglu Taner
Hashimotos thyroiditis is thought to result from the decreased of T helper type 2 (Th2) responses, leading to progressive destruction of thyrocytes. IFN-λ1, -λ2, and -λ3 (also known as IL-29, IL-28A, and IL-28B, respectively) is a recently described member of the IFN-λ family and has been shown to decrease production of Th2 cytokines in vitro. However, the role and mechanism of IFN-λ1 in Hashimotos thyroiditis remain unkno...